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Target General Information |
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Target ID |
T80338 |
Target Info
|
Target Name |
Activin receptor type IIB (ACVR2B) |
Synonyms |
Activin receptor type2B; Activin receptor type-2B; ACTRIIB; ACTR-IIB |
Target Type |
Literature-reported Target |
Gene Name |
ACVR2B |
Biochemical Class |
Kinase |
UniProt ID |
|
Target Interacting Proteins |
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Kinases |
[+] 1 Kinases |
+ |
Interacting Target Name |
Activin receptor type IB (ACVR1B) |
Patented-recorded Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
SKR2; Serine/threonine-protein kinase receptor R2; ALK-4; ALK4; ACVRLK4; ACTR-IB; Activin receptor-like kinase 4; Activin receptor type-1B |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[1] |
2 |
Co-purification |
[2] |
References |
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REF 1 |
Truncated activin type II receptors inhibit bioactivity by the formation of heteromeric complexes with activin type I. receptors. Exp Cell Res. 1996 May 1;224(2):323-34.
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REF 2 |
Activation of signalling by the activin receptor complex. Mol Cell Biol. 1996 Mar;16(3):1066-73.
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