Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T76914 Target Info
Target Name Voltage-gated potassium channel Kv1.3 (KCNA3)
Synonyms Voltage-gated potassium channel subunit Kv1.3; Voltage-gated Kv1.3 K(+) channel; Voltage-gated K(+) channel Kv1.3; Potassium channel Kv1.3; KCNA3; HuKIII; HPCN3; HLK3; HGK5
Target Type Clinical trial Target
Gene Name KCNA3
Biochemical Class Voltage-gated ion channel
UniProt ID
KCNA3_HUMAN 
Target Interacting Proteins  Top
Alpha-type channels [+] 1 Alpha-type channels +
Interacting Target Name Voltage-gated potassium channel Kv1.5 (KCNA5) Successful Target Interacting Protein Info
UniProt ID
KCNA5_HUMAN 
Synonyms Voltage-gatedpotassium channel subunit Kv1.5; Voltage-gated potassium channel subunit Kv1.5; Voltage-gated potassium channel HK2; Potassium voltage-gated channel subfamily A member 5; Potassium channel Kv1.5; HPCN1; HK2; 02-Sensitive Potassium Channel Kv1.5
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Co-fractionation [2]
Auxiliary transporters [+] 1 Auxiliary transporters +
Interacting Target Name Caveolin 1 (CAV1) Literature-reported Target Interacting Protein Info
UniProt ID
CAV1_HUMAN 
Synonyms Caveolin-1; Caveolin1; Cav-1; CAV
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [2]
2 Fluorescence Resonance Energy Transfer [3]
References  Top
REF 1 Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
REF 2 Kv1.5 association modifies Kv1.3 traffic and membrane localization. J Biol Chem. 2008 Mar 28;283(13):8756-64.
REF 3 Caveolin interaction governs Kv1.3 lipid raft targeting. Sci Rep. 2016 Mar 2;6:22453.

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