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Target General Information |
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Target ID |
T76024 |
Target Info
|
Target Name |
Complement C1s component (C1S) |
Synonyms |
Complement component 1 subcomponent s; Complement C1s subcomponent; C1-esterase; C1 esterase |
Target Type |
Successful Target |
Gene Name |
C1S |
Biochemical Class |
Peptidase |
UniProt ID |
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Target Interacting Proteins |
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Peptidases |
[+] 1 Peptidases |
+ |
Interacting Protein Name |
Complement C1r subcomponent (C1R) |
Interacting Protein |
Interacting Protein Info
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UniProt ID |
|
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[1] |
2 |
Affinity Capture-Western |
[2] |
3 |
Reconstituted Complex |
[3] |
References |
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REF 1 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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REF 2 |
Interaction of C1q and mannan-binding lectin (MBL) with C1r, C1s, MBL-associated serine proteases 1 and 2, and the MBL-associated protein MAp19. J Immunol. 2000 Jul 15;165(2):878-87.
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REF 3 |
The N-terminal CUB-epidermal growth factor module pair of human complement protease C1r binds Ca2+ with high affinity and mediates Ca2+-dependent i... J Biol Chem. 1999 Apr 2;274(14):9149-59.
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