Target Interacting Protein Information
Target General Information | Top | ||||
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Target ID | T74952 | Target Info | |||
Target Name | cAMP protein kinase type II-beta (PRKAR2B) | ||||
Synonyms | cAMP-dependent protein kinase type II-beta regulatory subunit; Type RIIbeta regulatory subunit of protein kinase A; RIIbeta subunit of cAMP-dependent protein kinase; PKA RIIbeta-subunit | ||||
Target Type | Literature-reported Target | ||||
Gene Name | PRKAR2B | ||||
Biochemical Class | Kinase | ||||
UniProt ID |
Target Interacting Proteins | Top | ||||
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Kinases | [+] 1 Kinases | + | |||
Interacting Protein Name | cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) | Interacting Protein | Interacting Protein Info | ||
UniProt ID | |||||
Synonyms | PKACA; PKA C-alpha; cAMP-dependent protein kinase catalytic subunit alpha | ||||
Evidence Score (E-score) | 5 Experimental Evidences | + | |||
1 | Affinity Capture-MS | [1] | |||
2 | Affinity Capture-MS | [2] | |||
3 | Affinity Capture-MS | [3] | |||
4 | Affinity Capture-Western | [4] | |||
5 | Yeast two hybrid | [5] | |||
Other proteins | [+] 1 Other proteins | + | |||
Interacting Protein Name | A-kinase anchor protein 7 isoforms alpha and beta (AKAP7) | Interacting Protein | Interacting Protein Info | ||
UniProt ID | |||||
Synonyms | AKAP15; AKAP18 | ||||
Evidence Score (E-score) | 3 Experimental Evidences | + | |||
1 | Affinity Capture-MS | [1] | |||
2 | Affinity Capture-MS | [2] | |||
3 | Yeast two hybrid | [6] |
References | Top | ||||
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REF 1 | Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509. | ||||
REF 2 | The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440. | ||||
REF 3 | A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712-23. | ||||
REF 4 | Plasmin overcomes resistance to prostaglandin E2 in fibrotic lung fibroblasts by reorganizing protein kinase A signaling. J Biol Chem. 2011 Sep 16;286(37):32231-43. | ||||
REF 5 | Pooled-matrix protein interaction screens using Barcode Fusion Genetics. Mol Syst Biol. 2016 Apr 22;12(4):863. | ||||
REF 6 | A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226. |
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