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Target General Information |
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Target ID |
T67163 |
Target Info
|
Target Name |
Orphan nuclear receptor NURR1 (NR4A2) |
Synonyms |
Transcriptionally-inducible nuclear receptor; Transcriptionally inducible nuclear receptor; TINUR; Nuclear receptor subfamily 4 group A member 2; NURR1; NOT; Immediate-early response protein NOT |
Target Type |
Literature-reported Target |
Gene Name |
NR4A2 |
Biochemical Class |
Nuclear hormone receptor |
UniProt ID |
|
Target Interacting Proteins |
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Nuclear hormone receptors |
[+] 1 Nuclear hormone receptors |
+ |
Interacting Target Name |
Retinoic acid receptor RXR-alpha (RXRA) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
RXRalpha; Retinoid X receptor alpha; Nuclear receptor subfamily 2 group B member 1; NR2B1 |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Reconstituted Complex |
[1] |
2 |
Yeast two hybrid |
[1] |
3 |
Yeast two hybrid |
[2] |
References |
Top |
REF 1 |
A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1. Genes Dev. 1995 Apr 1;9(7):769-82.
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REF 2 |
Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. Mol Cell Proteomics. 2005 Feb;4(2):205-13.
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