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| Target General Information |
Top |
| Target ID |
T64567 |
Target Info
|
| Target Name |
Carbonic anhydrase IX (CA-IX) |
| Synonyms |
Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; PMW1; P54/58N; Membrane antigen MN; MN; G250 antigen (MN/CA IX/G250); G250; Carbonic anhydrase 9; Carbonate dehydratase IX; CAIX |
| Target Type |
Clinical trial Target |
| Gene Name |
CA9 |
| Biochemical Class |
Alpha-carbonic anhydrase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Protein Name |
Cullin-associated NEDD8-dissociated protein 1 (CAND1) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
TIP120; TIP120A |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-Western |
[1] |
| 3 |
Affinity Capture-Western |
[2] |
| References |
Top |
| REF 1 |
Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells. J Proteome Res. 2013 Jan 4;12(1):282-92.
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| REF 2 |
Disclosing the Interaction of Carbonic Anhydrase IX with Cullin-Associated NEDD8-Dissociated Protein 1 by Molecular Modeling and Integrated Binding Measurements. ACS Chem Biol. 2017 Jun 16;12(6):1460-1465.
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