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Target General Information |
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Target ID |
T62184 |
Target Info
|
Target Name |
GABA transporter GAT-1 (SLC6A1) |
Synonyms |
Solute carrier family 6 member 1; Sodium- and chloride-dependent GABA transporter 1; GAT1; GAT-1; GABT1; GABATR; GABA transporter 1 |
Target Type |
Successful Target |
Gene Name |
SLC6A1 |
Biochemical Class |
Neurotransmitter:sodium symporter |
UniProt ID |
|
Target Interacting Proteins |
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Vesicle fusion pores |
[+] 1 Vesicle fusion pores |
+ |
Interacting Protein Name |
Syntaxin-1A (STX1A) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
HPC.1; P35.1; STX1; SYN1A |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[1] |
2 |
Affinity Capture-Western |
[2] |
3 |
Reconstituted Complex |
[2] |
References |
Top |
REF 1 |
Substrates regulate gamma-aminobutyric acid transporters in a syntaxin 1A-dependent manner. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5686-91.
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REF 2 |
Transport rates of GABA transporters: regulation by the N-terminal domain and syntaxin 1A. Nat Neurosci. 2000 Oct;3(10):998-1003.
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