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| Target General Information |
Top |
| Target ID |
T61243 |
Target Info
|
| Target Name |
Metabotropic glutamate receptor 7 (mGluR7) |
| Synonyms |
mGluR7; GPRC1G |
| Target Type |
Literature-reported Target |
| Gene Name |
GRM7 |
| Biochemical Class |
GPCR glutamate |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Protein Name |
PRKCA-binding protein (PICK1) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
PICK; PRKCABP |
| Evidence Score (E-score) |
4 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[1] |
| 3 |
Reconstituted Complex |
[2] |
| 4 |
Yeast two hybrid |
[1] |
| References |
Top |
| REF 1 |
PICK1 interacts with and regulates PKC phosphorylation of mGLUR7. J Neurosci. 2000 Oct 1;20(19):7252-7.
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| REF 2 |
The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs. J Biol Chem. 2002 May 3;277(18):15221-4.
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