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| Target General Information |
Top |
| Target ID |
T60930 |
Target Info
|
| Target Name |
Insulin-like growth factor-I (IGF1) |
| Synonyms |
SomatomedinC; Somatomedin-C; Mechano growth factor; Insulin-like growth factor I; IGFI; IGF-I |
| Target Type |
Clinical trial Target |
| Gene Name |
IGF1 |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
Insulin-like growth factor-binding protein 3 (IGFBP3) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
IGFBP-3; IGF-binding protein 3; IBP-3; IBP3 |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| 3 |
Reconstituted Complex |
[3] |
| References |
Top |
| REF 1 |
Inactivation of the acid labile subunit gene in mice results in mild retardation of postnatal growth despite profound disruptions in the circulating insulin-like growth factor system. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6868-73.
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| REF 2 |
Type Ialpha collagen is an IGFBP-3 binding protein. Growth Horm IGF Res. 2003 Apr-Jun;13(2-3):89-97.
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| REF 3 |
Insulin-like growth factor (IGF)-binding protein 5 forms an alternative ternary complex with IGFs and the acid-labile subunit. J Biol Chem. 1998 Mar 13;273(11):6074-9.
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