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| Target General Information |
Top |
| Target ID |
T60897 |
Target Info
|
| Target Name |
Protein tyrosine phosphatase IVA 2 (PRL-2) |
| Synonyms |
Protein-tyrosine phosphatase of regenerating liver 2; Protein-tyrosine phosphatase 4a2; Protein tyrosine phosphatase type IVA 2; PTPCAAX2; PTP(CAAXII); PRL2; OV-1; HU-PP-1; BM-008 |
| Target Type |
Literature-reported Target |
| Gene Name |
PTP4A2 |
| Biochemical Class |
Phosphoric monoester hydrolase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Alpha-type channels |
[+] 4 Alpha-type channels |
+ |
| Interacting Protein Name |
Metal transporter CNNM4 (CNNM4) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
ACDP4 |
| Evidence Score (E-score) |
6 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-MS |
[2] |
| 3 |
Affinity Capture-MS |
[3] |
| 4 |
Affinity Capture-MS |
[4] |
| 5 |
Affinity Capture-MS |
[5] |
| 6 |
Proximity Label-MS |
[5] |
| Interacting Protein Name |
Metal transporter CNNM2 (CNNM2) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
ACDP2 |
| Evidence Score (E-score) |
4 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[4] |
| 2 |
Affinity Capture-MS |
[2] |
| 3 |
Affinity Capture-MS |
[5] |
| 4 |
Proximity Label-MS |
[5] |
| Interacting Protein Name |
Metal transporter CNNM3 (CNNM3) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
ACDP3 |
| Evidence Score (E-score) |
4 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[4] |
| 2 |
Affinity Capture-MS |
[3] |
| 3 |
Affinity Capture-MS |
[5] |
| 4 |
Proximity Label-MS |
[5] |
| Interacting Protein Name |
Metal transporter CNNM1 (CNNM1) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
ACDP1; CLP.1 |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[5] |
| 2 |
Affinity Capture-MS |
[2] |
| 3 |
Proximity Label-MS |
[5] |
| References |
Top |
| REF 1 |
Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Cell Rep. 2016 Nov 22;17(9):2488-2501.
|
| REF 2 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
|
| REF 3 |
Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol. 2007;3:89.
|
| REF 4 |
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Mol Cell Proteomics. 2016 Sep;15(9):3030-44.
|
| REF 5 |
Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics. Cell Syst. 2017 Apr 26;4(4):430-444.e5.
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