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| Target General Information |
Top |
| Target ID |
T59122 |
Target Info
|
| Target Name |
Surface glycoprotein LFA-3 (CD58) |
| Synonyms |
Surface glycoprotein LFA3; Lymphocyte functionassociated antigen 3; Lymphocyte function-associated antigen 3; LFA3; Ag3 |
| Target Type |
Successful Target |
| Gene Name |
CD58 |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
T-cell surface antigen CD2 (CD2) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
T-cell surface antigen T11/Leu-5; SRBC; Rosette receptor; LFA-3 receptor; LFA-2; Erythrocyte receptor |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Co-crystal Structure |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Molecular dissection of the CD2-CD58 counter-receptor interface identifies CD2 Tyr86 and CD58 Lys34 residues as the functional "hot spot". J Mol Biol. 2001 Sep 28;312(4):711-20.
|
| REF 2 |
A secreted protein microarray platform for extracellular protein interaction discovery. Anal Biochem. 2012 Jan 15;420(2):127-38.
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