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| Target General Information |
Top |
| Target ID |
T51693 |
Target Info
|
| Target Name |
Melanoma-associated antigen 3 (MAGEA3) |
| Synonyms |
Melanoma associated antigen-A3; Melanoma antigen 3; MAGE3; MAGE-A3 antigen; MAGE-A3; MAGE-3 antigen; Cancer/testis antigen 1.3; CT1.3; Antigen MZ2-D |
| Target Type |
Clinical trial Target |
| Gene Name |
MAGEA3 |
| Biochemical Class |
Melanoma associated antigen |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Acyltransferases |
[+] 1 Acyltransferases |
+ |
| Interacting Target Name |
Transcription intermediary factor 1-beta (TRIM28) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Tripartite motif-containing protein 28; TIF1-beta; TIF1B; RNF96; RING-type E3 ubiquitin transferase TIF1-beta; RING finger protein 96; Nuclear corepressor KAP-1; KRIP-1; KRAB-interacting protein 1; KRAB-associated protein 1; KAP-1; KAP1; E3 SUMO-protein ligase TRIM28 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Yeast two hybrid |
[2] |
| References |
Top |
| REF 1 |
MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases. Mol Cell. 2010 Sep 24;39(6):963-74.
|
| REF 2 |
Identification of novel small molecules that inhibit protein-protein interactions between MAGE and KAP-1. Arch Biochem Biophys. 2011 Apr 15;508(2):217-21.
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