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| Target General Information |
Top |
| Target ID |
T49102 |
Target Info
|
| Target Name |
NIMA-related kinase 2 (NEK2) |
| Synonyms |
Serine/threonine-protein kinase Nek2; NimA-related protein kinase 2; NimA-like protein kinase 1; Never in mitosis A-related kinase 2; NLK1; NEK2A; HSPK 21 |
| Target Type |
Literature-reported Target |
| Gene Name |
NEK2 |
| Biochemical Class |
Kinase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Protein Name |
Kinetochore protein NDC80 homolog (NDC80) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
HEC; HEC1; HsHec1; KNTC2; TID3; hsNDC80 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Biochemical Activity |
[1] |
| 2 |
Yeast two hybrid |
[2] |
| References |
Top |
| REF 1 |
Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation. J Biol Chem. 2002 Dec 20;277(51):49408-16.
|
| REF 2 |
A directed protein interaction network for investigating intracellular signal transduction. Sci Signal. 2011 Sep 6;4(189):rs8.
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