Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T47966 Target Info
Target Name GN-binding protein G(I)/G(S)/G(O) gamma-7 (GNG7)
Synonyms Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7; GNGT7; G protein gamma 7
Target Type Literature-reported Target
Gene Name GNG7
UniProt ID
GBG7_HUMAN 
Target Interacting Proteins  Top
Auxiliary transporters [+] 1 Auxiliary transporters +
Interacting Protein Name G protein subunit beta 1 (GNB1) Interacting Protein Interacting Protein Info
UniProt ID
GBB1_HUMAN 
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Protein-Fragment Complementation Assay [2]
3 Yeast two hybrid [3]
Beta-transducin repeats [+] 3 Beta-transducin repeats +
Interacting Protein Name G protein subunit beta-2 (GNB2) Interacting Protein Interacting Protein Info
UniProt ID
GBB2_HUMAN 
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Yeast two hybrid [3]
Interacting Protein Name Transducin beta chain 3 (GNB3) Interacting Protein Interacting Protein Info
UniProt ID
GBB3_HUMAN 
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Yeast two hybrid [3]
Interacting Protein Name Guanine nucleotide-binding protein subunit beta-5 (GNB5) Interacting Protein Interacting Protein Info
UniProt ID
GNB5_HUMAN 
Synonyms GB5
Evidence Score (E-score) 2 Experimental Evidences +
1 Co-localization [4]
2 Yeast two hybrid [3]
References  Top
REF 1 Gbeta3 forms distinct dimers with specific Ggamma subunits and preferentially activates the beta3 isoform of phospholipase C. Cell Signal. 2009 May;21(5):737-44.
REF 2 Novel GNB1 mutations disrupt assembly and function of G protein heterotrimers and cause global developmental delay in humans. Hum Mol Genet. 2017 Mar 15;26(6):1078-1086.
REF 3 Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families. J Biol Chem. 1996 Mar 22;271(12):7141-6.
REF 4 Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.

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