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| Target General Information |
Top |
| Target ID |
T47366 |
Target Info
|
| Target Name |
Activin receptor type IIA (ACVR2A) |
| Synonyms |
Activin receptor type2A; Activin receptor type-2A; ACVR2; ACTRIIA; ACTR-IIA |
| Target Type |
Clinical trial Target |
| Gene Name |
ACVR2A |
| Biochemical Class |
Kinase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Growth factors |
[+] 1 Growth factors |
+ |
| Interacting Protein Name |
Inhibin beta A chain (INHBA) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
EDF; FRP |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| 3 |
Reconstituted Complex |
[3] |
| References |
Top |
| REF 1 |
Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature. 2000 Mar 23;404(6776):411-4.
|
| REF 2 |
Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors. Cell. 1993 Nov 19;75(4):671-80.
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| REF 3 |
A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor beta, or bone morphogenic ... J Biol Chem. 1993 Jun 15;268(17):12719-23.
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