Target Interacting Protein Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T47351 | Target Info | |||
| Target Name | ADP-ribosylation factor 1 (ARF1) | ||||
| Synonyms | PVNH8 | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | ARF1 | ||||
| Biochemical Class | Small GTPase | ||||
| UniProt ID | |||||
| Target Interacting Proteins | Top | ||||
|---|---|---|---|---|---|
| Ester hydrolases | [+] 1 Ester hydrolases | + | |||
| Interacting Target Name | Phospholipase D1 (PLD1) | Patented-recorded Target | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | PLD 1; Phosphatidylcholine-hydrolyzing phospholipase D1; HPLD1; Choline phosphatase 1 | ||||
| Evidence Score (E-score) | 2 Experimental Evidences | + | |||
| 1 | Affinity Capture-Western | [1] | |||
| 2 | Co-fractionation | [2] | |||
| Other proteins | [+] 3 Other proteins | + | |||
| Interacting Protein Name | Coatomer subunit beta (COPB1) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | COPB | ||||
| Evidence Score (E-score) | 3 Experimental Evidences | + | |||
| 1 | Affinity Capture-Western | [3] | |||
| 2 | Co-localization | [4] | |||
| 3 | Yeast two hybrid | [5] | |||
| Interacting Protein Name | ADP-ribosylation factor-binding protein GGA3 (GGA3) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Evidence Score (E-score) | 3 Experimental Evidences | + | |||
| 1 | Reconstituted Complex | [6] | |||
| 2 | Yeast two hybrid | [6] | |||
| 3 | Yeast two hybrid | [7] | |||
| Interacting Protein Name | ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | ARF1GAP; HRIHFB2281 | ||||
| Evidence Score (E-score) | 2 Experimental Evidences | + | |||
| 1 | Co-fractionation | [2] | |||
| 2 | Reconstituted Complex | [4] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Activation of phospholipase D1 by direct interaction with ADP-ribosylation factor 1 and RalA. FEBS Lett. 1998 Jul 3;430(3):231-5. | ||||
| REF 2 | Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44. | ||||
| REF 3 | ARF1 regulates Nef-induced CD4 degradation. Curr Biol. 2004 Jun 22;14(12):1056-64. | ||||
| REF 4 | Mutational analysis of the Arf1*GTP/Arf GAP interface reveals an Arf1 mutant that selectively affects the Arf GAP ASAP1. Curr Biol. 2005 Dec 6;15(23):2164-9. | ||||
| REF 5 | COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP. EMBO J. 2000 Aug 1;19(15):3905-17. | ||||
| REF 6 | GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex. J Cell Biol. 2000 Apr 3;149(1):81-94. | ||||
| REF 7 | The GGAs promote ARF-dependent recruitment of clathrin to the TGN. Cell. 2001 Apr 6;105(1):93-102. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.