Target Interacting Protein Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T46871 | Target Info | |||
| Target Name | SH2 domain inositol 5'-phosphatase 1 (INPP5D) | ||||
| Synonyms | p150Ship; hp51CN; SIP145; SIP-145; SHIP1; SHIP-1; SHIP; SH2 domaincontaining inositol phosphatase 1; SH2 domaincontaining inositol 5'phosphatase 1; SH2 domain-containing inositol phosphatase 1; SH2 domain-containing inositol 5'-phosphatase 1; Phosphatidylinositol 3,4,5trisphosphate 5phosphatase 1; Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; Inositol polyphosphate5phosphatase of 145 kDa; Inositol polyphosphate-5-phosphatase of 145 kDa | ||||
| Target Type | Clinical trial Target | ||||
| Gene Name | INPP5D | ||||
| Biochemical Class | Phosphoric monoester hydrolase | ||||
| UniProt ID | |||||
| Target Interacting Proteins | Top | ||||
|---|---|---|---|---|---|
| Adapter proteins | [+] 1 Adapter proteins | + | |||
| Interacting Protein Name | Growth factor receptor-bound protein 2 (GRB2) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | SH2/SH3 adapter GRB2; Protein Ash; Growth factor receptor-bound protein 2; ASH; Adapter protein GRB2 | ||||
| Evidence Score (E-score) | 2 Experimental Evidences | + | |||
| 1 | Affinity Capture-Western | [1] | |||
| 2 | Protein-peptide | [1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2. Curr Biol. 1996 Apr 1;6(4):438-45. | ||||
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