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| Target General Information |
Top |
| Target ID |
T42822 |
Target Info
|
| Target Name |
Ferrochelatase (FECH) |
| Synonyms |
Protoheme ferro-lyase; Heme synthetase; FECH |
| Target Type |
Successful Target |
| Gene Name |
FECH |
| Biochemical Class |
Ferrochelatase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Ester hydrolases |
[+] 1 Ester hydrolases |
+ |
| Interacting Target Name |
Serine/threonine PP2A-alpha (PPP2CA) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; RP-C; Replication protein C; PP2A-alpha |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Proximity Label-MS |
[2] |
| References |
Top |
| REF 1 |
Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Cell Rep. 2016 Nov 22;17(9):2488-2501.
|
| REF 2 |
Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics. Cell Syst. 2017 Apr 26;4(4):430-444.e5.
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