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| Target General Information |
Top |
| Target ID |
T42533 |
Target Info
|
| Target Name |
Nucleoside diphosphate kinase A (NM23-H1) |
| Synonyms |
nm23H1; Tumor metastatic processassociated protein; Tumor metastatic process-associated protein; NM23; NDPKA; NDP kinase A; NDK A; Metastasis inhibition factor nm23; Granzyme Aactivated DNase; Granzyme A-activated DNase; GAAD |
| Target Type |
Literature-reported Target |
| Gene Name |
NME1 |
| Biochemical Class |
Kinase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Protein Name |
Nucleoside diphosphate kinase B (NME2) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
NDKB; NDPK.B; NDPKB; NM23.H2; NM23B; PUF |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Yeast two hybrid |
[2] |
| References |
Top |
| REF 1 |
NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling. J Biol Chem. 2007 Apr 20;282(16):12075-96.
|
| REF 2 |
Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol. 2011 Oct 11;7:536.
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