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| Target General Information |
Top |
| Target ID |
T38453 |
Target Info
|
| Target Name |
Zinc finger E-box-binding homeobox 2 (ZEB2) |
| Synonyms |
Zinc finger homeobox protein 1b; ZFX1B; ZFHX1B; Smad-interacting protein 1; SMADIP1; SIP1; KIAA0569; HRIHFB2411 |
| Target Type |
Literature-reported Target |
| Gene Name |
ZEB2 |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Transcription regulators |
[+] 1 Transcription regulators |
+ |
| Interacting Target Name |
Mothers against decapentaplegic homolog 3 (SMAD3) |
Preclinical Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
TGF-beta response effector Smad3; Smad3; SMAD family member 3; SMAD 3; Mothers against DPP homolog 3; MMad3; MADH3; Mad3; MAD homolog 3; JV15-2; HSMAD3; HMAD-3 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Yeast two hybrid |
[2] |
| References |
Top |
| REF 1 |
Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin. J Biol Chem. 2005 Oct 21;280(42):35477-89.
|
| REF 2 |
Functional proteomics mapping of a human signaling pathway. Genome Res. 2004 Jul;14(7):1324-32. Validation Studies
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