Target Interacting Protein Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T37417 | Target Info | |||
| Target Name | NDR2 protein kinase (STK38L) | ||||
| Synonyms | Serine/threonine-protein kinase 38-like; Nuclear Dbf2-related kinase 2; NDR2; KIAA0965 | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | STK38L | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Target Interacting Proteins | Top | ||||
|---|---|---|---|---|---|
| Other proteins | [+] 2 Other proteins | + | |||
| Interacting Protein Name | MOB kinase activator 2 (MOB2) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | HCCA2 | ||||
| Evidence Score (E-score) | 6 Experimental Evidences | + | |||
| 1 | Affinity Capture-MS | [1] | |||
| 2 | Affinity Capture-MS | [2] | |||
| 3 | Affinity Capture-MS | [3] | |||
| 4 | Affinity Capture-MS | [4] | |||
| 5 | Affinity Capture-Western | [5] | |||
| 6 | Affinity Capture-Western | [1] | |||
| Interacting Protein Name | MOB kinase activator 1B (MOB1B) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | MATS2; MOB4A; MOBKL1A | ||||
| Evidence Score (E-score) | 3 Experimental Evidences | + | |||
| 1 | Affinity Capture-MS | [1] | |||
| 2 | Affinity Capture-MS | [4] | |||
| 3 | Affinity Capture-Western | [1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases. J Biol Chem. 2004 Jun 4;279(23):24444-51. | ||||
| REF 2 | Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy. Sci Signal. 2015 Apr 7;8(371):rs3. | ||||
| REF 3 | Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509. | ||||
| REF 4 | Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1. Mol Syst Biol. 2013 Dec 22;9:713. | ||||
| REF 5 | Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases. Mol Cell Biol. 2010 Sep;30(18):4507-20. | ||||
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