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| Target General Information |
Top |
| Target ID |
T36935 |
Target Info
|
| Target Name |
Prostate specific antigen (KLK3) |
| Synonyms |
Seminin; Semenogelase; Prostate-specific antigen; PSA; P-30 antigen; Kallikrein-3; Gamma-seminoprotein; APS |
| Target Type |
Clinical trial Target |
| Gene Name |
KLK3 |
| Biochemical Class |
Peptidase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 2 Other proteins |
+ |
| Interacting Protein Name |
Plasma serine protease inhibitor (SERPINA5) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
PAI.3; PAI3; PCI; PCI.B; PLANH3; PROCI |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| 3 |
Co-purification |
[2] |
| Interacting Protein Name |
Alpha-2-macroglobulin (A2M) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
A2MD; CPAMD5; FWP007; S863.7 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[3] |
| 2 |
Co-localization |
[4] |
| References |
Top |
| REF 1 |
Complex formation between protein C inhibitor and prostate-specific antigen in vitro and in human semen. Eur J Biochem. 1994 Feb 15;220(1):45-53.
|
| REF 2 |
Characterization of semenogelin II and its molecular interaction with prostate-specific antigen and protein C inhibitor. Eur J Biochem. 1996 May 15;238(1):88-96.
|
| REF 3 |
Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors. Eur J Biochem. 1990 Dec 27;194(3):755-63.
|
| REF 4 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
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