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| Target General Information |
Top |
| Target ID |
T30040 |
Target Info
|
| Target Name |
Vascular endothelial growth factor B (VEGFB) |
| Synonyms |
VRF; VEGF-related factor; VEGF-B |
| Target Type |
Successful Target |
| Gene Name |
VEGFB |
| Biochemical Class |
Growth factor |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Growth factors |
[+] 1 Growth factors |
+ |
| Interacting Target Name |
Vascular endothelial growth factor A (VEGFA) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
VPF; VEGF-A; VEGF; Vascular permeability factor; Vascular endothelial growth factor A |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-MS |
[2] |
| 3 |
Co-localization |
[3] |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Target Name |
Vascular endothelial growth factor receptor 1 (FLT-1) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
VEGFR-1; VEGFR1; VEGF-1 receptor; Vascular permeability factor receptor; Tyrosine-protein kinase receptor FLT; Tyrosine-protein kinase FRT; FRT; Fms-like tyrosine kinase 1; FLT |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[4] |
| 2 |
Reconstituted Complex |
[4] |
| References |
Top |
| REF 1 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
|
| REF 2 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440.
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| REF 3 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
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| REF 4 |
Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11709-14.
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