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| Target General Information |
Top |
| Target ID |
T27826 |
Target Info
|
| Target Name |
Spectrin non-erythroid beta chain 1 (SPTBN1) |
| Synonyms |
Spectrin, non-erythroid beta chain 1; Spectrin beta chain, non-erythrocytic 1; SPTB2; Fodrin beta chain; Beta-II spectrin |
| Target Type |
Clinical trial Target |
| Gene Name |
SPTBN1 |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
Synuclein alpha (SNCA) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
PARK1; Non-A4 component of amyloid precursor; NonA4 component of amyloid precursor; Non-A beta component of AD amyloid; NonA beta component of AD amyloid; NACP |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Co-localization |
[2] |
| 3 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. Mol Cell Proteomics. 2008 Nov;7(11):2123-37.
|
| REF 2 |
-Synuclein modulates neurite outgrowth by interacting with SPTBN1. Biochem Biophys Res Commun. 2012 Aug 3;424(3):497-502.
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