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| Target General Information |
Top |
| Target ID |
T26846 |
Target Info
|
| Target Name |
Phospholipase C-beta-1 (PLCB1) |
| Synonyms |
Phospholipase C-beta1; Phospholipase C-I; Phosphoinositide phospholipase C-beta-1; Phosphoinositide phospholipase C; PLC-beta-1; PLC-I; PLC-154; KIAA0581; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 |
| Target Type |
Literature-reported Target |
| Gene Name |
PLCB1 |
| Biochemical Class |
Phosphoric diester hydrolase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Guanine nucleotide-binding |
[+] 1 Guanine nucleotide-binding |
+ |
| Interacting Target Name |
Guanine nucleotide-binding alpha-q (GNAQ) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
GNAQ; G alphaq; G alpha(q) |
| Evidence Score (E-score) |
4 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Biochemical Activity |
[2] |
| 3 |
Fluorescence Resonance Energy Transfer |
[1] |
| 4 |
Reconstituted Complex |
[1] |
| References |
Top |
| REF 1 |
Stable association between G alpha(q) and phospholipase C beta 1 in living cells. J Biol Chem. 2006 Aug 18;281(33):23999-4014.
|
| REF 2 |
A unique fold of phospholipase C-beta mediates dimerization and interaction with G alpha q. Nat Struct Biol. 2002 Jan;9(1):32-6.
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