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| Target General Information |
Top |
| Target ID |
T26226 |
Target Info
|
| Target Name |
Prolactin receptor (PRLR) |
| Synonyms |
PRL-R |
| Target Type |
Clinical trial Target |
| Gene Name |
PRLR |
| Biochemical Class |
Cytokine receptor |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Protein Name |
Proto-oncogene vav (VAV1) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
VAV |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Vav is necessary for prolactin-stimulated proliferation and is translocated into the nucleus of a T-cell line. J Biol Chem. 1995 Jun 2;270(22):13246-53.
|
| REF 2 |
Activation and association of the Tec tyrosine kinase with the human prolactin receptor: mapping of a Tec/Vav1-receptor binding site. Mol Endocrinol. 2001 May;15(5):832-41.
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