Content Navigation
( All
None )
| Target General Information |
Top |
| Target ID |
T24587 |
Target Info
|
| Target Name |
O-6-methylguanine-DNA-alkyltransferase (MGMT) |
| Synonyms |
Methylated-DNA--protein-cysteine methyltransferase; Human O(6)-alkylguanine-DNA alkyltransferase; 6-O-methylguanine-DNA methyltransferase |
| Target Type |
Clinical trial Target |
| Gene Name |
MGMT |
| Biochemical Class |
Methyltransferase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
Proliferating cell nuclear antigen (PCNA) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Cyclin |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| 3 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Proteomic analysis of human O6-methylguanine-DNA methyltransferase by affinity chromatography and tandem mass spectrometry. Biochem Biophys Res Commun. 2005 Dec 2;337(4):1176-84.
|
| REF 2 |
S-phase Specific Downregulation of Human O6-Methylguanine DNA Methyltransferase (MGMT) and its Serendipitous Interactions with PCNA and p21cip1 Proteins in Glioma Cells. Neoplasia. 2018 Apr;20(4):305-323.
|
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.
