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| Target General Information |
Top |
| Target ID |
T22978 |
Target Info
|
| Target Name |
Transforming growth factor beta 3 (TGFB3) |
| Synonyms |
Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3; TGF-beta-3; Latency-associated peptide |
| Target Type |
Clinical trial Target |
| Gene Name |
TGFB3 |
| Biochemical Class |
Growth factor |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Target Name |
TGF-beta receptor type II (TGFBR2) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Transforminggrowth factor-beta receptor type II; Transforming growth factor-beta receptor type II; TGFR-2; TGF-beta type II receptor; TGF-beta receptor type-2; TbetaR-II |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Co-crystal Structure |
[2] |
| References |
Top |
| REF 1 |
Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. J Biol Chem. 1999 Jan 8;274(2):584-94.
|
| REF 2 |
Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex. Nat Struct Biol. 2002 Mar;9(3):203-8.
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