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| Target General Information |
Top |
| Target ID |
T22350 |
Target Info
|
| Target Name |
Endoglin CD105 (ENG) |
| Synonyms |
Endoglin; END; CD105 |
| Target Type |
Clinical trial Target |
| Gene Name |
ENG |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 2 Kinases |
+ |
| Interacting Target Name |
TGF-beta receptor type I (TGFBR1) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Type I TGFbeta receptor kinase; Transforming growth factor-beta receptor type I; TGFR-1; TGF-beta type I receptor; TGF-beta receptor type-1; TbetaR-I; TbetaRI; SKR4; Serine/threonine-protein kinase receptor R4; ALK-5; ALK5; Activin receptor-like kinase 5; Activin A receptor type II-like protein kinase of 53kD |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Biochemical Activity |
[1] |
| Interacting Target Name |
TGF-beta receptor type II (TGFBR2) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Transforminggrowth factor-beta receptor type II; Transforming growth factor-beta receptor type II; TGFR-2; TGF-beta type II receptor; TGF-beta receptor type-2; TbetaR-II |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Biochemical Activity |
[1] |
| References |
Top |
| REF 1 |
Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II. J Biol Chem. 2002 Aug 9;277(32):29197-209.
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