Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T20498 Target Info
Target Name RalA binding protein 1 (RALBP1)
Synonyms RalBP1; RalA-binding protein 1; Ral-interacting protein 1; RLIP76; RLIP1; Dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; 76 kDa Ral-interacting protein
Target Type Literature-reported Target
Gene Name RALBP1
Biochemical Class Non ABC multidrug exporter
UniProt ID
RBP1_HUMAN 
Target Interacting Proteins  Top
Acid anhydride hydrolases [+] 2 Acid anhydride hydrolases +
Interacting Protein Name Ras-related protein Ral-A (RALA) Interacting Protein Interacting Protein Info
UniProt ID
RALA_HUMAN 
Synonyms RAL
Evidence Score (E-score) 3 Experimental Evidences +
1 Co-localization [1]
2 Reconstituted Complex [2]
3 Yeast two hybrid [3]
Interacting Protein Name Ras-related protein Ral-B (RALB) Interacting Protein Interacting Protein Info
UniProt ID
RALB_HUMAN 
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [4]
2 Yeast two hybrid [3]
Transcription regulators [+] 1 Transcription regulators +
Interacting Protein Name G protein pathway suppressor 2 (GPS2) Interacting Protein Interacting Protein Info
UniProt ID
GPS2_HUMAN 
Synonyms AMF.1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [5]
2 Yeast two hybrid [6]
Other proteins [+] 3 Other proteins +
Interacting Protein Name RalBP1-associated Eps domain-containing protein 1 (REPS1) Interacting Protein Interacting Protein Info
UniProt ID
REPS1_HUMAN 
Synonyms RALBP1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [5]
2 Co-fractionation [7]
Interacting Protein Name RalBP1-associated Eps domain-containing protein 2 (REPS2) Interacting Protein Interacting Protein Info
UniProt ID
REPS2_HUMAN 
Synonyms POB1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [5]
2 Affinity Capture-Western [8]
Interacting Protein Name TCF3 fusion partner (TFPT) Interacting Protein Interacting Protein Info
UniProt ID
TFPT_HUMAN 
Synonyms FB1; INO80F; amida
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [5]
2 Yeast two hybrid [9]
References  Top
REF 1 Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
REF 2 Effector recognition by the small GTP-binding proteins Ras and Ral. J Biol Chem. 1999 Jun 18;274(25):17763-70.
REF 3 Ral GTPases regulate exocyst assembly through dual subunit interactions. J Biol Chem. 2003 Dec 19;278(51):51743-8.
REF 4 RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly. Cell. 2011 Jan 21;144(2):253-67.
REF 5 Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
REF 6 Next-generation sequencing to generate interactome datasets. Nat Methods. 2011 Jun;8(6):478-80.
REF 7 Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
REF 8 Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral. J Biol Chem. 1998 Jan 9;273(2):814-21.
REF 9 A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226.

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