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| Target General Information |
Top |
| Target ID |
T20186 |
Target Info
|
| Target Name |
Cardiac troponin I (TNNI3) |
| Synonyms |
TNNI3 |
| Target Type |
Literature-reported Target |
| Gene Name |
TNNI3 |
| Biochemical Class |
Troponin |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
Troponin C (TN-C) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Troponin C, slow skeletal and cardiac muscles; TNNC |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Co-crystal Structure |
[1] |
| 2 |
Protein-peptide |
[2] |
| 3 |
Reconstituted Complex |
[3] |
| References |
Top |
| REF 1 |
Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridil. J Biol Chem. 2002 Aug 23;277(34):31124-33.
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| REF 2 |
Kinetic studies of calcium and cardiac troponin I peptide binding to human cardiac troponin C using NMR spectroscopy. Eur Biophys J. 2002 Jul;31(4):245-56.
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| REF 3 |
A cross-linking study of the N-terminal extension of human cardiac troponin I. Biochemistry. 2003 Sep 2;42(34):10324-32.
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