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| Target General Information |
Top |
| Target ID |
T19492 |
Target Info
|
| Target Name |
Voltage-gated potassium channel Kv1.2 (KCNA2) |
| Synonyms |
Voltage-gated potassium channel subunit Kv1.2; Voltage-gated potassium channel HBK5; Voltage-gated K(+) channel HuKIV; Potassium voltage-gated channel subfamily A member 2; NGK1 |
| Target Type |
Literature-reported Target |
| Gene Name |
KCNA2 |
| Biochemical Class |
Voltage-gated ion channel |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Protein Name |
Src substrate cortactin (CTTN) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
EMS1 |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Fluorescence Resonance Energy Transfer |
[2] |
| 3 |
Reconstituted Complex |
[1] |
| References |
Top |
| REF 1 |
Tyrosine phosphorylation of Kv1.2 modulates its interaction with the actin-binding protein cortactin. J Biol Chem. 2002 Oct 11;277(41):38596-606.
|
| REF 2 |
An essential role for cortactin in the modulation of the potassium channel Kv1.2. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17412-7.
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