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| Target General Information |
Top |
| Target ID |
T18904 |
Target Info
|
| Target Name |
Lysine-specific demethylase 4A (KDM4A) |
| Synonyms |
KIAA0677; Jumonji domain-containing protein 2A; JmjC domain-containing histone demethylation protein 3A; JMJD2A; JMJD2; JHDM3A |
| Target Type |
Patented-recorded Target |
| Gene Name |
KDM4A |
| Biochemical Class |
Paired donor oxygen oxidoreductase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Histones |
[+] 1 Histones |
+ |
| Interacting Protein Name |
Histone H3.1 (H31) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
H3/A; H3FA |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Biochemical Activity |
[1] |
| 2 |
Co-crystal Structure |
[2] |
| 3 |
Protein-peptide |
[2] |
| References |
Top |
| REF 1 |
The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Nature. 2006 Jul 20;442(7100):312-6.
|
| REF 2 |
Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A. Science. 2006 May 5;312(5774):748-51.
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