Target Interacting Protein Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T15053 | Target Info | |||
| Target Name | Lactate dehydrogenase A (LDHA) | ||||
| Synonyms | Renal carcinoma antigen NYREN59; Renal carcinoma antigen NY-REN-59; PIG19; Llactate dehydrogenase A chain; LDHM; LDH-M; LDH-A; LDH muscle subunit; L-lactate dehydrogenase A chain; Cell proliferationinducing gene 19 protein; Cell proliferation-inducing gene 19 protein | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | LDHA | ||||
| Biochemical Class | CH-OH donor oxidoreductase | ||||
| UniProt ID | |||||
| Target Interacting Proteins | Top | ||||
|---|---|---|---|---|---|
| Oxidoreductases | [+] 2 Oxidoreductases | + | |||
| Interacting Protein Name | L-lactate dehydrogenase B chain (LDHB) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | HEL.S.281; LDH.B; LDH.H; LDHBD; TRG.5 | ||||
| Evidence Score (E-score) | 5 Experimental Evidences | + | |||
| 1 | Affinity Capture-MS | [1] | |||
| 2 | Co-fractionation | [2] | |||
| 3 | Yeast two hybrid | [3] | |||
| 4 | Yeast two hybrid | [4] | |||
| 5 | Yeast two hybrid | [5] | |||
| Interacting Target Name | Superoxide dismutase Cu-Zn (SOD Cu-Zn) | Clinical trial Target | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | Superoxide dismutase 1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase; hSod1 | ||||
| Evidence Score (E-score) | 2 Experimental Evidences | + | |||
| 1 | Affinity Capture-MS | [6] | |||
| 2 | Co-fractionation | [7] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509. | ||||
| REF 2 | A census of human soluble protein complexes. Cell. 2012 Aug 31;150(5):1068-81. | ||||
| REF 3 | Next-generation sequencing to generate interactome datasets. Nat Methods. 2011 Jun;8(6):478-80. | ||||
| REF 4 | A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226. | ||||
| REF 5 | Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol. 2011 Oct 11;7:536. | ||||
| REF 6 | A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-B Signaling. Cell Syst. 2017 Dec 27;5(6):564-577.e12. | ||||
| REF 7 | Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44. | ||||
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