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| Target General Information |
Top |
| Target ID |
T10383 |
Target Info
|
| Target Name |
Phospholipase D2 (PLD2) |
| Synonyms |
hPLD2; Phosphatidylcholine-hydrolyzing phospholipase D2; PLD1C; PLD 2; Choline phosphatase 2 |
| Target Type |
Clinical trial Target |
| Gene Name |
PLD2 |
| Biochemical Class |
Phosphoric diester hydrolase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Auxiliary transporters |
[+] 1 Auxiliary transporters |
+ |
| Interacting Target Name |
Caveolin 1 (CAV1) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Caveolin-1; Caveolin1; Cav-1; CAV |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Co-fractionation |
[2] |
| References |
Top |
| REF 1 |
Aquaporin 3 colocates with phospholipase d2 in caveolin-rich membrane microdomains and is downregulated upon keratinocyte differentiation. J Invest Dermatol. 2003 Dec;121(6):1487-95.
|
| REF 2 |
Phospholipase D2: functional interaction with caveolin in low-density membrane microdomains. FEBS Lett. 2000 Feb 11;467(2-3):326-32.
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