Target Interacting Protein Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T06792 | Target Info | |||
| Target Name | Proteasome beta-9 (PS beta-9) | ||||
| Synonyms | Really interesting new gene 12 protein; RING12; Proteasome subunit beta-1i; Proteasome subunit beta type-9; Proteasome chain 7; PSMB6i; Multicatalytic endopeptidase complex chain 7; Macropain chain 7; Low molecular mass protein 2; LMP2 | ||||
| Target Type | Patented-recorded Target | ||||
| Gene Name | PSMB9 | ||||
| Biochemical Class | Peptidase | ||||
| UniProt ID | |||||
| Target Interacting Proteins | Top | ||||
|---|---|---|---|---|---|
| Acid anhydride hydrolases | [+] 1 Acid anhydride hydrolases | + | |||
| Interacting Protein Name | Proteasome 26S subunit ATPase 5 (PSMC5) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | S8; SUG.1; SUG1; TBP10; TRIP1; p45; p45/SUG | ||||
| Evidence Score (E-score) | 3 Experimental Evidences | + | |||
| 1 | Affinity Capture-MS | [1] | |||
| 2 | Affinity Capture-MS | [2] | |||
| 3 | Co-localization | [3] | |||
| Peptidases | [+] 4 Peptidases | + | |||
| Interacting Target Name | Proteasome beta-5 (PS beta-5) | Patented-recorded Target | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | Proteasome subunit X; Proteasome subunit MB1; Proteasome subunit beta type-5; Proteasome epsilon chain; Proteasome chain 6; Multicatalytic endopeptidase complex epsilon chain; MB1; Macropain epsilon chain; LMPX | ||||
| Evidence Score (E-score) | 3 Experimental Evidences | + | |||
| 1 | Affinity Capture-MS | [1] | |||
| 2 | Affinity Capture-MS | [2] | |||
| 3 | Affinity Capture-Western | [4] | |||
| Interacting Target Name | Proteasome beta-2 (PS beta-2) | Patented-recorded Target | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | Proteasome subunit Z; Proteasome subunit beta type-7; Multicatalytic endopeptidase complex chain Z; Macropain chain Z | ||||
| Evidence Score (E-score) | 3 Experimental Evidences | + | |||
| 1 | Affinity Capture-MS | [1] | |||
| 2 | Affinity Capture-Western | [5] | |||
| 3 | Yeast two hybrid | [6] | |||
| Interacting Protein Name | Proteasome subunit beta type-2 (PSMB2) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | HC7.I | ||||
| Evidence Score (E-score) | 3 Experimental Evidences | + | |||
| 1 | Affinity Capture-MS | [1] | |||
| 2 | Affinity Capture-MS | [2] | |||
| 3 | Co-fractionation | [7] | |||
| Interacting Protein Name | Proteasome subunit alpha type-7 (PSMA7) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | C6; HSPC; RC6.1; XAPC7 | ||||
| Evidence Score (E-score) | 3 Experimental Evidences | + | |||
| 1 | Affinity Capture-MS | [1] | |||
| 2 | Affinity Capture-MS | [2] | |||
| 3 | Yeast two hybrid | [8] | |||
| Other proteins | [+] 1 Other proteins | + | |||
| Interacting Protein Name | Proteasome maturation protein (POMP) | Interacting Protein | Interacting Protein Info | ||
| UniProt ID | |||||
| Synonyms | C13orf12; PNAS.110; UMP1 | ||||
| Evidence Score (E-score) | 3 Experimental Evidences | + | |||
| 1 | Affinity Capture-MS | [1] | |||
| 2 | Affinity Capture-MS | [2] | |||
| 3 | Yeast two hybrid | [8] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509. | ||||
| REF 2 | The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440. | ||||
| REF 3 | The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription. EMBO J. 2006 Sep 20;25(18):4223-33. | ||||
| REF 4 | Novel propeptide function in 20 S proteasome assembly influences beta subunit composition. J Biol Chem. 2000 Aug 4;275(31):24156-62. | ||||
| REF 5 | Tumor cell lines expressing the proteasome subunit isoform LMP7E1 exhibit immunoproteasome deficiency. Cancer Res. 2006 Jan 15;66(2):649-52. | ||||
| REF 6 | The proteasome maturation protein POMP facilitates major steps of 20S proteasome formation at the endoplasmic reticulum. EMBO Rep. 2007 Dec;8(12):1170-5. | ||||
| REF 7 | Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44. | ||||
| REF 8 | Differential intra-proteasome interactions involving standard and immunosubunits. Biochem Biophys Res Commun. 2007 Jul 6;358(3):867-72. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.