Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T03581 Target Info
Target Name NDR1 protein kinase (STK38)
Synonyms Serine/threonine-protein kinase 38; Nuclear Dbf2-related kinase 1; NDR1
Target Type Literature-reported Target
Gene Name STK38
Biochemical Class Kinase
UniProt ID
STK38_HUMAN 
Target Interacting Proteins  Top
Other proteins [+] 2 Other proteins +
Interacting Protein Name MOB kinase activator 2 (MOB2) Interacting Protein Interacting Protein Info
UniProt ID
MOB2_HUMAN 
Synonyms HCCA2
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-Western [3]
4 Affinity Capture-Western [1]
Interacting Protein Name MOB kinase activator 1A (MOB1A) Interacting Protein Interacting Protein Info
UniProt ID
MOB1A_HUMAN 
Synonyms C2orf6; MATS1; MOB1; MOBK1B; MOBKL1B; Mob4B
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [2]
2 Affinity Capture-Western [3]
3 Affinity Capture-Western [4]
References  Top
REF 1 Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases. J Biol Chem. 2004 Jun 4;279(23):24444-51.
REF 2 Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy. Sci Signal. 2015 Apr 7;8(371):rs3.
REF 3 Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases. Mol Cell Biol. 2010 Sep;30(18):4507-20.
REF 4 Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein. J Biol Chem. 2004 Aug 20;279(34):35228-35.

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