Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T02318 Target Info
Target Name B-cell-activating factor (TNFSF13B)
Synonyms ZTNF4; UNQ401/PRO738; Tumor necrosis factor ligand superfamily member 13B; TNFSF20; TNF-and APOL-related leukocyte expressed ligand 1; TNF- and APOL-related leukocyte expressed ligand 1; TALL1; TALL-1; Dendritic cell-derived TNF-like molecule; CD257; BLyS; BAFF; B lymphocyte stimulator; B cell-activating factor
Target Type Successful Target
Gene Name TNFSF13B
Biochemical Class Cytokine: tumor necrosis factor
UniProt ID
TN13B_HUMAN 
Target Interacting Proteins  Top
Other proteins [+] 3 Other proteins +
Interacting Target Name B-cell-activating factor receptor (TNFRSF13C) Clinical trial Target Interacting Protein Info
UniProt ID
TR13C_HUMAN 
Synonyms Tumor necrosis factor receptor superfamily member 13C; CD268; BR3; BLyS receptor 3; BAFF-R; BAFFR; BAFF receptor; B cell-activating factor receptor
Evidence Score (E-score) 2 Experimental Evidences +
1 Co-crystal Structure [1]
2 Co-localization [2]
Interacting Target Name B-cell maturation protein (TNFRSF17) Successful Target Interacting Protein Info
UniProt ID
TNR17_HUMAN 
Synonyms Tumor necrosis factor receptor superfamily member 17; CD269; BCMA; BCM
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [3]
2 Co-crystal Structure [1]
Interacting Target Name Transmembrane activator and CAML interactor (TNFRSF13B) Clinical trial Target Interacting Protein Info
UniProt ID
TR13B_HUMAN 
Synonyms Tumor necrosis factor receptor superfamily member 13B; TACI; CD267
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [4]
2 Reconstituted Complex [4]
References  Top
REF 1 Ligand-receptor binding revealed by the TNF family member TALL-1. Nature. 2003 May 1;423(6935):49-56.
REF 2 Antibody deficiency associated with an inherited autosomal dominant mutation in TWEAK. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5127-32.
REF 3 B cell maturation protein is a receptor for the tumor necrosis factor family member TALL-1. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9156-61.
REF 4 Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS. J Biol Chem. 2000 Nov 10;275(45):35478-85.

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