Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T00973 Target Info
Target Name Polybromo-1 (PBRM1)
Synonyms hPB1; Protein polybromo-1; Polybromo-1D; PB1; BRG1-associated factor 180; BAF180
Target Type Literature-reported Target
Gene Name PBRM1
UniProt ID
PB1_HUMAN 
Target Interacting Proteins  Top
Acid anhydride hydrolases [+] 1 Acid anhydride hydrolases +
Interacting Target Name Mitotic growth and transcription activator (BAF190A) Literature-reported Target Interacting Protein Info
UniProt ID
SMCA4_HUMAN 
Synonyms Transcription activator BRG1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; SNF2L4; SNF2-beta; SNF2B; Protein BRG-1; Protein brahma homolog 1; BRG1-associated factor 190A; BRG1; ATP-dependent helicase SMARCA4
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-Western [2]
Transcription regulators [+] 3 Transcription regulators +
Interacting Protein Name AT-rich interactive domain-containing protein 2 (ARID2) Interacting Protein Interacting Protein Info
UniProt ID
ARID2_HUMAN 
Synonyms BAF200; p200
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [2]
2 Co-fractionation [3]
Interacting Protein Name SWI/SNF complex subunit SMARCC1 (SMARCC1) Interacting Protein Interacting Protein Info
UniProt ID
SMRC1_HUMAN 
Synonyms BAF155; CRACC1; Rsc8; SRG3; SWI3
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-Western [2]
Interacting Protein Name SWI/SNF complex subunit SMARCC2 (SMARCC2) Interacting Protein Interacting Protein Info
UniProt ID
SMRC2_HUMAN 
Synonyms BAF170; CRACC2; Rsc8
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-Western [2]
References  Top
REF 1 The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer. J Pathol. 2018 Jan;244(1):36-48.
REF 2 PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes. Genes Dev. 2005 Jul 15;19(14):1662-7.
REF 3 Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.

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