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| Target General Information |
Top |
| Target ID |
T00902 |
Target Info
|
| Target Name |
Neurotrophin-4 (NTF4) |
| Synonyms |
Neutrophic factor 4; Neurotrophin5; Neurotrophin4; Neurotrophin-5; NTF5; NT4; NT-5; NT-4 |
| Target Type |
Literature-reported Target |
| Gene Name |
NTF4 |
| Biochemical Class |
Growth factor |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Target Name |
BDNF/NT-3 growth factors receptor (TrkB) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Tropomyosin-related kinase B; TrkB tyrosine kinase; Trk-B; TRKB; Neurotrophic tyrosine kinase receptor type 2; GP145-TrkB |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Co-crystal Structure |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Specificity in Trk receptor:neurotrophin interactions: the crystal structure of TrkB-d5 in complex with neurotrophin-4/5. Structure. 2001 Dec;9(12):1191-9.
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| REF 2 |
A discrete domain of the human TrkB receptor defines the binding sites for BDNF and NT-4. Biochem Biophys Res Commun. 2002 Mar 1;291(3):501-7.
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