Target Regulator(s) Information (MicroRNA)

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Target General Information
The microRNAs (miRNAs) Regulating This Target
References
Target General Information  Top
Target ID T61657 Target Info
Target Name Retinoic acid receptor beta (RARB)
Synonyms RAR-epsilon; RAR-beta; Nuclear receptor subfamily 1 group B member 2; NR1B2; HBV-activated protein; HAP
Target Type Successful Target
Gene Name RARB
Biochemical Class Nuclear hormone receptor
UniProt ID
P10826
The microRNAs (miRNAs) Regulating This Target  Top
miRNA Mature ID hsa-miR-106a-5p miRNA Info
miRNA Mature AC
MIMAT0000103
Sequence aaaagugcuuacagugcagguag
miRNA Species Homo sapiens
Regulation Mechanism miR-106a directly targeted retinoic acid receptor beta (RARB) 3'UTR. [1]
Evidence Score (E-score) 1 +
1 Luciferase Reporter Assay; Western Blot [1]
Representative Target(s) Regulated by This miRNA Amyloid beta A4 protein (APP) Target Info
A4_HUMAN
Apoptosis mediating surface antigen FAS (FAS) Target Info
TNR6_HUMAN
miRNA Mature ID hsa-miR-146a-5p miRNA Info
miRNA Mature AC
MIMAT0000449
Sequence ugagaacugaauuccauggguu
miRNA Species Homo sapiens
Regulation Mechanism miR-146a directly target RARB 3'UTR. [2]
Evidence Score (E-score) 1 +
1 Luciferase Reporter Assay; Western Blot [2]
Representative Target(s) Regulated by This miRNA Activation B7-1 antigen (CD80) Target Info
CD80_HUMAN
Apoptosis mediating surface antigen FAS (FAS) Target Info
TNR6_HUMAN
miRNA Mature ID hsa-miR-146b-5p miRNA Info
miRNA Mature AC
MIMAT0002809
Sequence ugagaacugaauuccauaggcug
miRNA Species Homo sapiens
Regulation Mechanism miR-146b directly target RARB 3'UTR. [2]
Evidence Score (E-score) 1 +
1 Luciferase Reporter Assay; Western Blot [2]
Representative Target(s) Regulated by This miRNA Calgranulin D (S100A12) Target Info
S10AC_HUMAN
DNA-binding factor KBF1 (p105) Target Info
NFKB1_HUMAN
miRNA Mature ID hsa-miR-16-2-3p miRNA Info
miRNA Mature AC
MIMAT0004518
Sequence ccaauauuacugugcugcuuua
miRNA Species Homo sapiens
Regulation Mechanism miR-16-2 suppressed RARB expression but induced esophageal cancer proliferation. [3]
Evidence Score (E-score) 1 +
1 qRT-PCR; Western Blot [3]
Representative Target(s) Regulated by This miRNA Retinoic acid receptor beta (RARB) Target Info
RARB_HUMAN
References  Top
REF 1 miRNA-106a directly targeting RARB associates with the expression of Na(+)/I(-) symporter in thyroid cancer by regulating MAPK signaling pathway. J Exp Clin Cancer Res. 2016 Jun 24;35(1):101.
REF 2 Family of microRNA-146 Regulates RAR in Papillary Thyroid Carcinoma. PLoS One. 2016 Mar 24;11(3):e0151968.
REF 3 Prognostic significance of differentially expressed miRNAs in esophageal cancer. Int J Cancer. 2011 Jan 1;128(1):132-43.

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