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Target General Information |
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Target ID |
T51426 |
Target Info
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Target Name |
Farnesoid X-activated receptor (FXR) |
Synonyms |
Retinoid X receptor-interacting protein 14; RXR-interacting protein 14; RIP14; Nuclear receptor subfamily 1 group H member 4; HRR1; Farnesol receptor HRR-1; FXR; Bile acid receptor; BAR |
Target Type |
Successful Target |
Gene Name |
NR1H4 |
Biochemical Class |
Nuclear hormone receptor |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-192-3p |
miRNA Info
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miRNA Mature AC |
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Sequence |
cugccaauuccauaggucacag
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
miR-192-3p bound specifically to the NR1H4- 3'UTR and decreased luciferase activity. |
[1] |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay |
[1] |
Representative Target(s) Regulated by This miRNA |
Farnesoid X-activated receptor (FXR)
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Target Info
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References |
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REF 1 |
microRNA-192 suppresses the expression of the farnesoid X receptor. Am J Physiol Gastrointest Liver Physiol. 2016 Jun 1;310(11):G1044-51.
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