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| Target General Information |
Top |
| Target ID |
T45287 |
Target Info
|
| Target Name |
Aspartyl aminopeptidase (DNPEP) |
| Synonyms |
DAP; ASPEP |
| Target Type |
Clinical trial Target |
| Gene Name |
DNPEP |
| Biochemical Class |
Peptidase |
| UniProt ID |
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| The microRNAs (miRNAs) Regulating This Target |
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| miRNA Mature ID |
hsa-miR-140-5p |
miRNA Info
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| miRNA Mature AC |
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| Sequence |
cagugguuuuacccuaugguag
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| miRNA Species |
Homo sapiens |
| Evidence Score (E-score) |
2 |
+ |
| 1 |
Luciferase Reporter Assay |
[1] |
| 2 |
Western Blot |
[2] |
| Representative Target(s) Regulated by This miRNA |
Adenosine deaminase (ADA)
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Target Info
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|
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Aspartyl aminopeptidase (DNPEP)
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Target Info
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| References |
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| REF 1 |
Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling. Mol Cell Biol. 2011 Jul;31(14):3019-28.
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| REF 2 |
Profiling microRNA expression in murine bone healing and non-union formation: Role of miR-140 during the early stage of bone healing. PLoS One. 2019 Jul 19;14(7):e0218395.
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