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Target General Information |
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Target ID |
T25703 |
Target Info
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Target Name |
Heme oxygenase 1 (HMOX1) |
Synonyms |
HO1; HO-1; HO |
Target Type |
Clinical trial Target |
Gene Name |
HMOX1 |
Biochemical Class |
Paired donor oxygen oxidoreductase |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-122-5p |
miRNA Info
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miRNA Mature AC |
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Sequence |
uggagugugacaaugguguuug
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miRNA Species |
Homo sapiens |
Evidence Score (E-score) |
2 |
+ |
1 |
Microarray |
[1] |
2 |
Western Blot; qRT-PCR |
[2] |
Representative Target(s) Regulated by This miRNA |
Apoptosis regulator Bcl-W (BCL-W)
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Target Info
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Apoptosis regulator Bcl-xL (BCL-xL)
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Target Info
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References |
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REF 1 |
MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell. 2007 Jul 6;27(1):91-105.
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REF 2 |
miR-122-induced down-regulation of HO-1 negatively affects miR-122-mediated suppression of HBV. Biochem Biophys Res Commun. 2010 Aug 6;398(4):771-7.
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