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Target General Information |
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Target ID |
T21715 |
Target Info
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Target Name |
RNA-binding protein Musashi-1 (MSI1) |
Synonyms |
RNA-binding protein Musashi homolog 1; Musashi-1 |
Target Type |
Literature-reported Target |
Gene Name |
MSI1 |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-330-3p |
miRNA Info
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miRNA Mature AC |
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Sequence |
gcaaagcacacggccugcagaga
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
MSI1 is a direct target gene of miR-330-3p in gastric cancer cell. Overexpression of miR-330-3p promoted E-cadherin expression and inhibited the expression of N-cadherin, vimentin and snail. |
[1] |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay; Western Blot |
[1] |
Representative Target(s) Regulated by This miRNA |
E2F transcription factor 1 (E2F1)
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Target Info
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Extracellular matrix receptor III (CD44)
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Target Info
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References |
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REF 1 |
MiR-330-3p inhibits gastric cancer progression through targeting MSI1. Am J Transl Res. 2016 Nov 15;8(11):4802-4811.
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