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| Target General Information |
Top |
| Target ID |
T21038 |
Target Info
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| Target Name |
Pattern recognition receptor NOD1 (NOD1) |
| Synonyms |
Nucleotide-binding oligomerization domain-containing protein 1; Caspase recruitment domain-containing protein 4; CARD4 |
| Target Type |
Literature-reported Target |
| Gene Name |
NOD1 |
| UniProt ID |
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| The microRNAs (miRNAs) Regulating This Target |
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| miRNA Mature ID |
hsa-miR-1250-3p |
miRNA Info
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| miRNA Mature AC |
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| Sequence |
acauuuuccagcccauuca
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| miRNA Species |
Homo sapiens |
| Regulation Mechanism |
PPARG-miR-125a signaling axis in ECs plays a critical role in the regulation of inflammation-triggered angiogenesis through direct targeting of NOD1. |
[1] |
| Evidence Score (E-score) |
1 |
+ |
| 1 |
Luciferase Reporter Assay; Western Blot |
[1] |
| Representative Target(s) Regulated by This miRNA |
Pattern recognition receptor NOD1 (NOD1)
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Target Info
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Phosphatase and tensin homolog (PTEN)
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Target Info
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| References |
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| REF 1 |
Negative regulation of NOD1 mediated angiogenesis by PPAR-regulated miR-125a. Biochem Biophys Res Commun. 2017 Jan 1;482(1):28-34.
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