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Target General Information |
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Target ID |
T15033 |
Target Info
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Target Name |
C-X3-C chemokine receptor 1 (CX3CR1) |
Synonyms |
V28; GPR13; G-protein coupled receptor 13; Fractalkine receptor CX3CR1; Fractalkine receptor; CX3C chemokine receptor 1; CMKBRL1; CMKBLR1; CMK-BRL1; CMK-BRL-1; C-X3-C CKR-1; Beta chemokine receptor-like1; Beta chemokine receptor-like 1 |
Target Type |
Literature-reported Target |
Gene Name |
CX3CR1 |
Biochemical Class |
GPCR rhodopsin |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-296-3p |
miRNA Info
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miRNA Mature AC |
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Sequence |
gaggguuggguggaggcucucc
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
CX3CR1 gene was a direct regulator of tumorsuppressive miR-296-3p. |
[1] |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay; Western Blot |
[1] |
Representative Target(s) Regulated by This miRNA |
C-X3-C chemokine receptor 1 (CX3CR1)
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Target Info
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Intercellular adhesion molecule ICAM-1 (ICAM1)
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Target Info
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References |
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REF 1 |
miRNA-296-3p modulates chemosensitivity of lung cancer cells by targeting CX3CR1. Am J Transl Res. 2016 Apr 15;8(4):1848-56.
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