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Target General Information |
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Target ID |
T10491 |
Target Info
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Target Name |
C-X-C chemokine receptor type 7 (ACKR3) |
Synonyms |
RDC1; RDC-1; Gprotein coupled receptor RDC1 homolog; Gprotein coupled receptor 159; GPR159; G-protein coupled receptor RDC1 homolog; G-protein coupled receptor 159; Chemokine orphan receptor 1; CXCR7; CXCR-7; CXC-R7; CXC chemokine receptor type 7; CMKOR1; Atypical chemokine receptor 3 |
Target Type |
Preclinical Target |
Gene Name |
ACKR3 |
Biochemical Class |
GPCR rhodopsin |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-100-5p |
miRNA Info
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miRNA Mature AC |
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Sequence |
aacccguagauccgaacuugug
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
ACKR3 is a direct target gene of miR-100. |
[1] |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay; Western Blot |
[1] |
Representative Target(s) Regulated by This miRNA |
ATM serine/threonine kinase (ATM)
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Target Info
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Bone morphogenetic protein receptor (BMPR2)
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Target Info
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References |
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REF 1 |
miR-100 suppresses the proliferation and tumor growth of esophageal squamous cancer cells via targeting CXCR7. Oncol Rep. 2016 Jun;35(6):3453-9.
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