Target Binding Site Detail
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T10586 | Target Info | |||
| Target Name | Lysozyme (LYZ) | ||||
| Synonyms | Lysozyme C; LYZ; 1,4betaNacetylmuramidase C | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | LYZ | ||||
| Biochemical Class | Glycosylase | ||||
| UniProt ID | |||||
| Ligand General Information | Top | ||||
|---|---|---|---|---|---|
| Ligand Name | 2-(Acetylamino)-2-Deoxy-a-D-Glucopyranose | Ligand Info | |||
| Canonical SMILES | CC(=O)NC1C(C(C(OC1O)CO)O)O | ||||
| InChI | 1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8+/m1/s1 | ||||
| InChIKey | OVRNDRQMDRJTHS-PVFLNQBWSA-N | ||||
| PubChem Compound ID | 82313 | ||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| PDB ID: 7XF7 Crystal Structure of Human Lysozyme Complexed with N-Acetyl-alpha-D-Glucosamine | ||||||
| Method | X-ray diffraction | Resolution | 1.55 Å | Mutation | No | [1] |
| PDB Sequence |
KVFERCELAR
28 TLKRLGMDGY38 RGISLANWMC48 LAKWESGYNT58 RATNYNAGDR68 STDYGIFQIN 78 SRYWCNDGKT88 PGAVNACHLS98 CSALLQDNIA108 DAVACAKRVV118 RDPQGIRAWV 128 AWRNRCQNRD138 VRQYVQGCGV148
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| PDB ID: 7XF8 Crystal Structure of Human Lysozyme Complexed with N-Acetyl-alpha-D-Glucosamine | ||||||
| Method | X-ray diffraction | Resolution | 1.60 Å | Mutation | No | [1] |
| PDB Sequence |
KVFERCELAR
28 TLKRLGMDGY38 RGISLANWMC48 LAKWESGYNT58 RATNYNAGDR68 STDYGIFQIN 78 SRYWCNDGKT88 PGAVNACHLS98 CSALLQDNIA108 DAVACAKRVV118 RDPQGIRAWV 128 AWRNRCQNRD138 VRQYVQGCGV148
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Crystal Structure of Human Lysozyme Complexed with N-Acetyl-alpha-d-glucosamine.. doi:10.3390/app12094363. | ||||
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