Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T98635 | Target Info | |||
| Target Name | Angiopoietin-related protein 4 (ANGPTL4) | ||||
| Synonyms | UNQ171/PRO197; PSEC0166; PP1158; PGAR; Hepatic fibrinogen/angiopoietin-related protein; HFARP; Angiopoietin-like protein PP1158; Angiopoietin-like protein 4; Angiopoietin-like 4; ARP4 | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | ANGPTL4 | ||||
| Biochemical Class | Fibrinogen protein | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: Myristic acid | Ligand Info | |||||
| Structure Description | Human Angiopoietin-Like 4 C-Terminal Domain (cANGPTL4) with Myristic Acid | PDB:6U73 | ||||
| Method | X-ray diffraction | Resolution | 2.38 Å | Mutation | No | [1] |
| PDB Sequence |
PRDCQELFQV
194 GERQSGLFEI204 QPQGSPPFLV214 NCKMTSDGGW224 TVIQRRHDGS234 VDFNRPWEAY 244 KAGFGDPHGE254 FWLGLEKVHS264 ITGDRNSRLA274 VQLRDWDGNA284 ELLQFSVHLG 294 GEDTAYSLQL304 TAPVAGQLGA314 TTVPPSGLSV324 PFSTWDQDHD334 LRRDKNCAKS 344 LSGGWWFGTC354 SHSNLNGQYF364 RSIPQQRQKL374 KKGIFWKTWR384 GRYYPLQATT 394 MLIQPM
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Crystal Structures of Angiopoietin-Like 4s C-Terminal Domain (cANGPTL4) Reveal a Binding Site for Various Ligands | ||||
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